Investigating itch circuitry
نویسندگان
چکیده
منابع مشابه
The imagined itch: brain circuitry supporting nocebo-induced itch in atopic dermatitis patients.
BACKGROUND Psychological factors are known to significantly modulate itch in patients suffering from chronic itch. Itch is also highly susceptible to both placebo and nocebo (negative placebo) effects. Brain activity likely supports nocebo-induced itch, but is currently unknown. METHODS We collected functional MRI (fMRI) data from atopic dermatitis (AD) patients, in a within-subject design, a...
متن کاملInvestigating and treating sweet itch – approach and case studies
Sweet itch is an equine hypersensitivity reaction to the biting insects Simulium and Culicoides. It is the most common allergic skin disease of horses and there is a strong hereditary component with certain breeds being over-represented (Welsh, shire and Icelandic breeds). A seasonal pruritus of the predilection sites (mane and tail base) is the main clinical sign leading to self-inflicted trau...
متن کاملOA08.04. Brain circuitry subserving acupuncture relief of itch in atopic dermatitis: an fMRI study
Purpose Chronic itch is a prevalent symptom of many inflammatory skin disorders, including atopic dermatitis (AD). While conventional systemic approaches to reduce AD itch have shown limited efficacy and/or significant side effects, several recent studies have demonstrated effectiveness of acupuncture for reducing itch in healthy adults and AD. We sought to evaluate the brain circuitry underlyi...
متن کاملNew aspects of itch pathophysiology: component analysis of atopic itch using the 'Eppendorf Itch Questionnaire'.
Itch represents a leading symptom in dermatological practice with many psychophysiological aspects. Instruments for qualitative registration of these central nervous factors and evaluation of therapeutic measures are still missing. We analyzed in detail the subjective itch sensation in 108 patients with acute atopic eczema with a new questionnaire developed in analogy to the McGill pain questio...
متن کاملNeuropathic itch.
Chronic itch can be caused by dysfunctions of itch-sensing neurons that produce sensory hallucinations of pruritogenic stimuli. The cellular and molecular mechanisms are still unknown. All neurological disease categories have been implicated, and neurological causes should be considered for patients with otherwise-unexplained itch. The same neurological illnesses that cause neuropathic pain can...
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ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2013
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn3542